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 Dr. Eyal Dassau
Senior Investigator & Diabetes Team Research Manager
Adjunct Senior Investigator Sansum Diabetes Research Institute (SDRI)
Education
- BSc: 1999, ChE, Technion Israel Institute of Technology
- MSc: 2002, ChE, Technion Israel Institute of Technology
- PhD: 2006, ChE, Technion Israel Institute of Technology
Honors
- Otis William Postdoctoral Fellowship, 2008
Research
- Biomedical design and control: the application of process system engineering principles to design and control of automated insulin delivery system (artificial pancreatic β-cell) to improve glycemic control in type 1 diabetes mellitus patients
- Process and product design with emphasis on medical and biomedical applications
- Systems theory, modeling, simulation, optimization and control to medical, biological, and other complex systems
Publications (selected)
- Y. Wang, E. Dassau, H. Zisser, L. Jovanovič and F. J. Doyle III (2010),“ Automatic Bolus and Adaptive Basal (ABAB) Therapy”, Diabetes Technol. Ther. (Accepted).
- B. Grosman, E. Dassau, H. Zisser, L. Jovanovič and F. J. Doyle III (2010), “Zone MPC: A strategy to minimize hyper-and hypo-glycemic events”, Diabetes. Sci. Technol. (In Press).
- R. S. Mauseth, Y. Wang, E. Dassau, D. P. Matheson, H. Zisser, L. Jovanovič, and F. J. Doyle III (2010).“ Proposed Clinical Application for Tuning Fuzzy Logic Controller of Artificial Pancreas Utilizing a Personalization Factor”, Diabetes Sci. Technol. (In Press).
- F. Campos-Cornejo, D.U. Campos-Delgado , E. Dassau, D. Espinoza-Trejo, H. Zisser, L. Jovanovič and F J. Doyle III (2010). “An Advisory Protocol for a Dual Insulin Therapy Following Run-to-run Methodology”. Diabetes Technol. Ther. (Accepted).
- B. Buckingham, H. P. Chase, E. Dassau, E. Cobry, P. Clinton, V. Gage, J. Wilkinson, K. Caswell, F. Cameron, H. Lee, B. W. Bequette and F. J. Doyle III (2010). “Prevention of Nocturnal Hypoglycemia Using Predictive Alarm Algorithms and Insulin Pump Suspension”. Diabetes Care 33 (5) 1013-1017.
- E. Dassau, F. Cameron, H. Lee, B. W. Bequette, H. Zisser, L. Jovanovič, H. P. Chase, D. M. Willson, B. A. Buckingham and F. J. Doyle III (2010). “Real-time Hypoglycemia Prediction Using Continuous Glucose Monitoring (CGM), A Safety Net to the Artificial Pancreas”. Diabetes Care 33 (6) 1249-1254.
- R. A. Harvey, Y. Wang, B. Grosman, M. W. Percival, W. Bevier, D. A. Finan, H. Zisser, D. Seborg, L. Jovanovič , F. J. Doyle III and E. Dassau (2010). “The Quest for the Artificial Pancreas: Combining Technology with Treatment”. IEEE Eng. Med. Bio. 29 (2) 53-63.
- E. Dassau, E. Atlas and M. Phillip (2010). “Closing the loop”, Int J Clin Pract, 64(s166),20-25.
- E. Dassau, F. J. Doyle III, L. Jovanovič and H. Zisser (2009). “Enhanced 911/GPS Wizard for the Prevention of Severe Hypoglycemia – Monitor, Alert and Locate”, Diabetes Sci. Technol. 3(6), 1501-1506.
- H. Zisser, W. Bevier, E. Dassau and L. Jovanovič (2010). “Hydrostatic Effects on Continuous Subcutaneous Insulin Infusion (CSII) Pump Delivery Performance”. Diabetes. Sci. Technol. 4(1),98-103.
- Y. Wang, H. Zisser, E. Dassau, L. Jovanovič and F. J. Doyle III (2010). “Model Predictive Control with Learning-Type Set-point: Application to Artificial Pancreatic b-Cell”. AIChE J. 56(6). 1510-1518.
- B. Kovatchev, S. Patek, E. Dassau, F. J. Doyle III, L. Magni, G. De Nicolao, and C. Cobelli (2009). “Control-To-Range For Diabetes: Functionality And Modular Architecture”. Diabetes Sci. Technol. 3(5), 1058-1065.
- Y. Wang, M. W. Percival , E. Dassau, H. Zisser, L. Jovanovič and F. J. Doyle III (2009). “A Novel Adaptive Basal Therapy Based on Glucose value and Its Rate of Change”, Diabetes Sci. Technol. 3(5), 1099-1108.
- Y. Wang, E. Dassau and F. J. Doyle III (2010). “Closed-Loop Control of Artificial Pancreatic b -Cell in Type 1 Diabetes Mellitus Using Model Predictive Iterative Learning Control”. IEEE Trans. Biomed. Eng. 57(2),211-219.
- C. Ellingsen, E. Dassau, H. Zisser, B. Grosman, M. W. Percival, L. Jovanovič , and F. J. Doyle III (2009). “Safety constraints in an artificial b-cell: an implementation of Model Predictive Control (MPC) with Insulin-on-Board (IOB)”. Diabetes. Sci. Technol. 3(3), 536-544.
- M. W. Percival, E. Dassau., H. Zisser, L. Jovanovič, and Francis J. Doyle III (2009). “Closed-Loop Control of an Artificial Pancreatic b-Cell: a Practical Approach to Design and Implementation”. Ind. Eng. Chem. Res. 48,6059-6067.
- S. D. Patek, B. W. Bequette, M. Breton, B. A. Buckingham, E. Dassau, F. J. Doyle III, John Lum, L. Magni, and H. Zisser (2009). “In Silico Preclinical Trials: Methodology and Engineering Guide to Closed-Loop Control in T1DM” Diabetes Sci. Technol. 3(2), 269-282.
- J. Bondia, E. Dassau, H. Zisser, R. Calm, J. Vehí, L. Jovanovič, and F. J. Doyle III (2009). “Coordinated basal-bolus infusion for tighter postprandial glucose control in insulin pump therapy”, Diabetes Sci. Technol. 3(1), 89-97.
- E. Dassau, C. C. Palerm, H. Zisser, B. A. Buckingham, L. Jovanovič and F. J. Doyle III (2009). “In Silico Evaluation Platform for Artificial Pancreatic b-Cell Development – a Dynamic Simulator for Closed-Loop Control with Hardware-in-the-Loop”, Diabetes Technol. Ther. 11(3),187-194.
- E. Dassau, H. Zisser, C. C. Palerm, B. A. Buckingham, L. Jovanovič, and F. J. Doyle III (2008). “Modular Artificial b-Cell System: A Prototype for Clinical Research”, Diabetes Sci. Technol. 2(5), 863-872.
- H. Zisser, L. Robinson, W. Bevier, E. Dassau, C. Ellingsen, F.J. Doyle III and L. Jovanovič (2008). “Bolus Calculator: A Review of Four “Smart” Insulin Pumps.” Diabetes. Technol. Ther. 10(6),441-444.
- E. Dassau, B. W. Bequette, B. A. Buckingham and F. J. Doyle III (2008). “Detection of a Meal Using Continuous Glucose Monitoring (CGM): Implications for an Artificial β-cell.” Diabetes Care 31(2), 295-300.
News
Contact Information
Chemical Engineering Dept.
Mail Code 5080
University of California
Santa Barbara, CA 93106-5080 USA
Office Location: 3228 Engineering II
dassau@engineering.ucsb.edu
Phone:(805)693-4727 (direct), (805)893-3120 (lab)
Fax: (805)893-4731
Links
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